Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing

Neutrophil (PMN) infiltration of the intestinal mucosa is a hallmark of tissue injury associated with inflammatory bowel diseases (IBDs). The pathological effects of PMNs are largely attributed to the release of soluble mediators and reactive oxygen species (ROS). We identified what we believe is a...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Autores principales: Butin-Israeli, Veronika, Bui, Triet M., Wiesolek, Hannah L., Mascarenhas, Lorraine, Lee, Joseph J., Mehl, Lindsey C., Knutson, Kaitlyn R., Adam, Stephen A., Goldman, Robert D., Beyder, Arthur, Wiesmuller, Lisa, Hanauer, Stephen B., Sumagin, Ronen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355304/
https://ncbi.nlm.nih.gov/pubmed/30640176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122085
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