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Neutrophil microparticles deliver active myeloperoxidase to injured mucosa to inhibit epithelial wound healing

Neutrophil (PMN) infiltration of the intestinal mucosa often leads to severe epithelial injury, however how this process occurs is unclear. The current work describes a novel mechanism, whereby membrane derived microparticles released by tissue infiltrating PMNs (PMN-MPs) serve as shuttles to protec...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Slater, Thomas W., Finkielsztein, Ariel, Mascarenhas, Lorraine A., Mehl, Lindsey C., Butin-Israeli, Veronika, Sumagin, Ronen
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5360559/
https://ncbi.nlm.nih.gov/pubmed/28242649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601810
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