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Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing

Neutrophil (PMN) infiltration of the intestinal mucosa is a hallmark of tissue injury associated with inflammatory bowel diseases (IBDs). The pathological effects of PMNs are largely attributed to the release of soluble mediators and reactive oxygen species (ROS). We identified what we believe is a...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Butin-Israeli, Veronika, Bui, Triet M., Wiesolek, Hannah L., Mascarenhas, Lorraine, Lee, Joseph J., Mehl, Lindsey C., Knutson, Kaitlyn R., Adam, Stephen A., Goldman, Robert D., Beyder, Arthur, Wiesmuller, Lisa, Hanauer, Stephen B., Sumagin, Ronen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355304/
https://ncbi.nlm.nih.gov/pubmed/30640176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122085
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