Neutrophil-induced genomic instability impedes resolution of inflammation and wound healing

Neutrophil (PMN) infiltration of the intestinal mucosa is a hallmark of tissue injury associated with inflammatory bowel diseases (IBDs). The pathological effects of PMNs are largely attributed to the release of soluble mediators and reactive oxygen species (ROS). We identified what we believe is a...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Butin-Israeli, Veronika, Bui, Triet M., Wiesolek, Hannah L., Mascarenhas, Lorraine, Lee, Joseph J., Mehl, Lindsey C., Knutson, Kaitlyn R., Adam, Stephen A., Goldman, Robert D., Beyder, Arthur, Wiesmuller, Lisa, Hanauer, Stephen B., Sumagin, Ronen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355304/
https://ncbi.nlm.nih.gov/pubmed/30640176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122085
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