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Progressing from Recurring Tissue Injury to Genomic Instability: A New Mechanism of Neutrophil Pathogenesis

Aberrant neutrophil (PMN) infiltration of the intestinal mucosa is a hallmark of inflammatory bowel diseases, including Crohn's disease and ulcerative colitis. While the genotoxic function of PMNs and its implications in carcinogenesis have been primarily associated with oxidative stress, recen...

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Pubblicato in:DNA Cell Biol
Autori principali: Bui, Triet M., Sumagin, Ronen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc., publishers 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7643757/
https://ncbi.nlm.nih.gov/pubmed/31188020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2019.4842
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