Deposition of microparticles by neutrophils onto inflamed epithelium: a new mechanism to disrupt epithelial intercellular adhesions and promote transepithelial migration

Neutrophil [polymorphonuclear leukocyte (PMN)] transepithelial migration (TEM) is a hallmark of inflammatory mucosal disorders. PMN TEM is associated with epithelial injury; however, mechanisms involved in this process are not well defined. The current work describes a new mechanism whereby depositi...

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Udgivet i:FASEB J
Main Authors: Butin-Israeli, Veronika, Houser, Madelyn C., Feng, Mingli, Thorp, Edward B., Nusrat, Asma, Parkos, Charles A., Sumagin, Ronen
Format: Artigo
Sprog:Inglês
Udgivet: Federation of American Societies for Experimental Biology 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5102120/
https://ncbi.nlm.nih.gov/pubmed/27553226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201600734R
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