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Coaching from the sidelines: the nuclear periphery in genome regulation

The genome is packaged and organized nonrandomly within the 3D space of the nucleus to promote efficient gene expression and to faithfully maintain silencing of heterochromatin. The genome is enclosed within the nucleus by the nuclear envelope membrane, which contains a set of proteins that actively...

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Pubblicato in:Nat Rev Genet
Autori principali: Buchwalter, Abigail, Kaneshiro, Jeanae M., Hetzer, Martin W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6355253/
https://ncbi.nlm.nih.gov/pubmed/30356165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41576-018-0063-5
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