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Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress

The inner nuclear membrane (INM) is a subdomain of the endoplasmic reticulum (ER) that is gated by the nuclear pore complex. It is unknown whether proteins of the INM and ER are degraded through shared or distinct pathways in mammalian cells. We applied dynamic proteomics to profile protein half-liv...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Buchwalter, Abigail, Schulte, Roberta, Tsai, Hsiao, Capitanio, Juliana, Hetzer, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802967/
https://ncbi.nlm.nih.gov/pubmed/31599721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49796
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