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Selective clearance of the inner nuclear membrane protein emerin by vesicular transport during ER stress

The inner nuclear membrane (INM) is a subdomain of the endoplasmic reticulum (ER) that is gated by the nuclear pore complex. It is unknown whether proteins of the INM and ER are degraded through shared or distinct pathways in mammalian cells. We applied dynamic proteomics to profile protein half-liv...

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Bibliografske podrobnosti
izdano v:eLife
Main Authors: Buchwalter, Abigail, Schulte, Roberta, Tsai, Hsiao, Capitanio, Juliana, Hetzer, Martin
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802967/
https://ncbi.nlm.nih.gov/pubmed/31599721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49796
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