The inner nuclear membrane protein Emerin regulates β-catenin activity by restricting its accumulation in the nucleus

Emerin is a type II inner nuclear membrane (INM) protein of unknown function. Emerin function is likely to be important because, when it is mutated, emerin promotes both skeletal muscle and heart defects. Here we show that one function of Emerin is to regulate the flux of β-catenin, an important tra...

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Bibliografiska uppgifter
Huvudupphovsmän: Markiewicz, Ewa, Tilgner, Katarzyna, Barker, Nick, van de Wetering, Mark, Clevers, Hans, Dorobek, Margareth, Hausmanowa-Petrusewicz, Irena, Ramaekers, Frans C S, Broers, Jos L V, Blankesteijn, W Matthijs, Salpingidou, Georgia, Wilson, Robert G, Ellis, Juliet A, Hutchison, Christopher J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523183/
https://ncbi.nlm.nih.gov/pubmed/16858403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601230
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