A novel role for the nuclear membrane protein emerin in association of the centrosome to the outer nuclear membrane

The type II inner nuclear membrane protein emerin is a component of the LINC complex that connects the nuclear lamina to the actin cytoskeleton. In emerin-null or -deficient human dermal fibroblasts we find that the centrosome is detached from the nucleus. Moreover, following siRNA knockdown of emer...

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Hlavní autoři: Salpingidou, Georgia, Smertenko, Andrei, Hausmanowa-Petrucewicz, Irena, Hussey, Patrick J., Hutchison, Chris J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2007
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064615/
https://ncbi.nlm.nih.gov/pubmed/17785515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200702026
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