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Tyrosine phosphorylation of nuclear-membrane protein emerin by Src, Abl and other kinases

X-linked recessive Emery-Dreifuss muscular dystrophy (EDMD) is caused by loss of emerin, a nuclear-membrane protein with roles in nuclear architecture, gene regulation and signaling. Phosphoproteomic studies have identified 13 sites of tyrosine phosphorylation in emerin. We validated one study, conf...

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Bibliografske podrobnosti
Main Authors: Tifft, Kathryn E., Bradbury, Katherine A., Wilson, Katherine L.
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2758807/
https://ncbi.nlm.nih.gov/pubmed/19789182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.048397
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