Sumoylated protein tyrosine phosphatase 1B localizes to the inner nuclear membrane and regulates the tyrosine phosphorylation of emerin

Protein tyrosine phosphatase (PTP)1B is an abundant non-transmembrane enzyme that plays a major role in regulating insulin and leptin signaling. Recently, we reported that PTP1B is inhibited by sumoylation, and that sumoylated PTP1B accumulates in a perinuclear distribution, consistent with its know...

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Bibliografiska uppgifter
Huvudupphovsmän: Yip, Shu-Chin, Cotteret, Sophie, Chernoff, Jonathan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Company of Biologists 2012
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283870/
https://ncbi.nlm.nih.gov/pubmed/22266903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.086256
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