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STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis
Innate immune activation contributes to the transition from nonalcoholic fatty liver to nonalcoholic steatohepatitis (NASH). Stimulator of IFN genes (STING, also referred to Tmem173) is a universal receptor that recognizes released DNA and triggers innate immune activation. In this work, we investig...
Gespeichert in:
| Veröffentlicht in: | J Clin Invest |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355218/ https://ncbi.nlm.nih.gov/pubmed/30561388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121842 |
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