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STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis
Innate immune activation contributes to the transition from nonalcoholic fatty liver to nonalcoholic steatohepatitis (NASH). Stimulator of IFN genes (STING, also referred to Tmem173) is a universal receptor that recognizes released DNA and triggers innate immune activation. In this work, we investig...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355218/ https://ncbi.nlm.nih.gov/pubmed/30561388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI121842 |
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