Caspase-11–Mediated Hepatocytic Pyroptosis Promotes the Progression of Nonalcoholic Steatohepatitis

BACKGROUND: Nonalcoholic steatohepatitis (NASH) is an inflammatory disease with severe outcomes. Hepatocyte death, including apoptosis, necrosis, and pyroptosis, has been implicated in pathophysiology of NASH. Pyroptosis is mediated by inflammasome activation pathways including caspase-1–mediated ca...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Mol Gastroenterol Hepatol
Prif Awduron: Zhu, Yingwei, Zhao, Han, Lu, Jian, Lin, Kai, Ni, Jingbin, Wu, Gaojue, Tang, Hong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2021
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261017/
https://ncbi.nlm.nih.gov/pubmed/33894425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2021.04.009
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