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Matrix stiffness regulates vascular integrity through focal adhesion kinase activity
Tumor vasculature is known to be more permeable than the vasculature found in healthy tissue, which in turn can lead to a more aggressive tumor phenotype and impair drug delivery into tumors. While the stiffening of the stroma surrounding solid tumors has been reported to increase vascular permeabil...
Kaydedildi:
| Yayımlandı: | FASEB J |
|---|---|
| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Federation of American Societies for Experimental Biology
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6355084/ https://ncbi.nlm.nih.gov/pubmed/30102569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800841R |
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