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Matrix Stiffness Enhances VEGFR-2 Internalization, Signaling, and Proliferation in Endothelial Cells

Vascular endothelial growth factor (VEGF) can mediate endothelial cell migration, proliferation, and angiogenesis. During cancer progression, VEGF production is often increased to stimulate the growth of new blood vessels to supply growing tumors with the additional oxygen and nutrients they require...

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Detalhes bibliográficos
Publicado no:Converg Sci Phys Oncol
Main Authors: LaValley, Danielle J., Zanotelli, Matthew R., Bordeleau, Francois, Wang, Wenjun, Schwager, Samantha C., Reinhart-King, Cynthia A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844494/
https://ncbi.nlm.nih.gov/pubmed/29531793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/2057-1739/aa9263
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