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Matrix Stiffness Enhances VEGFR-2 Internalization, Signaling, and Proliferation in Endothelial Cells

Vascular endothelial growth factor (VEGF) can mediate endothelial cell migration, proliferation, and angiogenesis. During cancer progression, VEGF production is often increased to stimulate the growth of new blood vessels to supply growing tumors with the additional oxygen and nutrients they require...

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Détails bibliographiques
Publié dans:Converg Sci Phys Oncol
Auteurs principaux: LaValley, Danielle J., Zanotelli, Matthew R., Bordeleau, Francois, Wang, Wenjun, Schwager, Samantha C., Reinhart-King, Cynthia A.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844494/
https://ncbi.nlm.nih.gov/pubmed/29531793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/2057-1739/aa9263
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