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Establishment of a transgenic mouse to model ETV7 expressing human tumors

The ETS transcription factor ETV7 has been characterized as a hematopoietic oncoprotein, which requires cooperating mutations for its leukemogenic activity. Although the ETV7 gene is highly conserved among vertebrates, part of the rodents, including Mus musculus, deleted the Etv7 gene locus. Many hu...

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Detalhes bibliográficos
Publicado no:Transgenic Res
Main Authors: Numata, Masashi, Klein Geltink, R. I., Grosveld, Gerard C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353817/
https://ncbi.nlm.nih.gov/pubmed/30478527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-018-0104-z
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