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Establishment of a transgenic mouse model specifically expressing human serum amyloid A in adipose tissue.

Obesity and obesity co-morbidities are associated with a low grade inflammation and elevated serum levels of acute phase proteins, including serum amyloid A (SAA). In the non-acute phase in humans, adipocytes are major producers of SAA but the function of adipocyte-derived SAA is unknown. To clarify...

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Detalhes bibliográficos
Main Authors: Maja Olsson, Sofie Ahlin, Bob Olsson, Per-Arne Svensson, Marcus Ståhlman, Jan Borén, Lena M S Carlsson, Kajsa Sjöholm
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3097194?pdf=render
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