Establishment of a transgenic mouse model with liver-specific expression of secretory immunoglobulin D

Mutation of mevalonate kinase (MVK) is thought to account for most cases of hyperimmunoglobulinemia D syndrome (HIDS) with recurrent fever. However, its mechanism and the relationship between elevated serum immunoglobulin D (IgD) and the clinical features of HIDS are unclear. In this study, we gener...

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Detalhes bibliográficos
Publicado no:Sci China Life Sci
Main Authors: Wang, Ping, Wei, ZhiGuo, Yan, BoWen, Huang, Tan, Gou, KeMian, Dai, YunPing, Zheng, Min, Wang, MeiLi, Cheng, XueQian, Wang, XiFeng, Xu, Chen, Sun, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Science China Press 2012
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7089205/
https://ncbi.nlm.nih.gov/pubmed/22527518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11427-012-4301-3
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