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Paths to stemness: building the ultimate antitumour T cell

Stem cells are defined by the ability to self-renew and to generate differentiated progeny, qualities that are maintained by evolutionarily conserved pathways that can lead to cancer when deregulated. There is now evidence that these stem cell-like attributes and signalling pathways are also shared...

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Detalles Bibliográficos
Publicado en:Nat Rev Cancer
Main Authors: Gattinoni, Luca, Klebanoff, Christopher A., Restifo, Nicholas P.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352980/
https://ncbi.nlm.nih.gov/pubmed/22996603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3322
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