The bystander effect contributes to the accumulation of senescent cells in vivo

Senescent cells accumulate with age in multiple tissues and may cause age‐associated disease and functional decline. In vitro, senescent cells induce senescence in bystander cells. To see how important this bystander effect may be for accumulation of senescent cells in vivo, we xenotransplanted sene...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: da Silva, Paulo F. L., Ogrodnik, Mikolaj, Kucheryavenko, Olena, Glibert, Julien, Miwa, Satomi, Cameron, Kerry, Ishaq, Abbas, Saretzki, Gabriele, Nagaraja‐Grellscheid, Sushma, Nelson, Glyn, von Zglinicki, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351849/
https://ncbi.nlm.nih.gov/pubmed/30462359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12848
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