Key role of SMN/SYNCRIP and RNA-Motif 7 in spinal muscular atrophy: RNA-Seq and motif analysis of human motor neurons

Spinal muscular atrophy is a motor neuron disorder caused by mutations in SMN1. The reasons for the selective vulnerability of motor neurons linked to SMN (encoded by SMN1) reduction remain unclear. Therefore, we performed deep RNA sequencing on human spinal muscular atrophy motor neurons to detect...

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Bibliografiske detaljer
Udgivet i:Brain
Main Authors: Rizzo, Federica, Nizzardo, Monica, Vashisht, Shikha, Molteni, Erika, Melzi, Valentina, Taiana, Michela, Salani, Sabrina, Santonicola, Pamela, Di Schiavi, Elia, Bucchia, Monica, Bordoni, Andreina, Faravelli, Irene, Bresolin, Nereo, Comi, Giacomo Pietro, Pozzoli, Uberto, Corti, Stefania
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351774/
https://ncbi.nlm.nih.gov/pubmed/30649277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awy330
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