Impaired non-homologous end joining in human primary alveolar type II cells in emphysema

Emphysema is characterized by alveolar wall destruction induced mainly by cigarette smoke. Oxidative damage of DNA may contribute to the pathophysiology of this disease. We studied the impairment of the non-homologous end joining (NHEJ) repair pathway and DNA damage in alveolar type II (ATII) cells...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Kosmider, Beata, Lin, Chih-Ru, Vlasenko, Liudmila, Marchetti, Nathaniel, Bolla, Sudhir, Criner, Gerard J., Messier, Elise, Reisdorph, Nichole, Powell, Roger L., Madesh, Muniswamy, Kelsen, Steven, Xander, Nathaniel, Correll, Kelly A., Mason, Robert J., Bahmed, Karim
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351635/
https://ncbi.nlm.nih.gov/pubmed/30696938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37000-z
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