The cytoprotective role of DJ-1 and p45 NFE2 against human primary alveolar type II cell injury and emphysema

Emphysema is characterized by irreversibly enlarged airspaces and destruction of alveolar walls. One of the factors contributing to this disease pathogenesis is an elevation in extracellular matrix (ECM) degradation in the lung. Alveolar type II (ATII) cells produce and secrete pulmonary surfactants...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Tan, Li Hui, Bahmed, Karim, Lin, Chih-Ru, Marchetti, Nathaniel, Bolla, Sudhir, Criner, Gerard J., Kelsen, Steven, Madesh, Muniswamy, Kosmider, Beata
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824795/
https://ncbi.nlm.nih.gov/pubmed/29476075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21790-3
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