Mitochondrial dysfunction in human primary alveolar type II cells in emphysema

BACKGROUND: Cigarette smoke is the main risk factor of pulmonary emphysema development, which is characterized by alveolar wall destruction. Mitochondria are important for alveolar type II (ATII) cell metabolism due to ATP generation. METHODS: We isolated ATII cells from control non-smoker and smoke...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Kosmider, Beata, Lin, Chih-Ru, Karim, Loukmane, Tomar, Dhanendra, Vlasenko, Liudmila, Marchetti, Nathaniel, Bolla, Sudhir, Madesh, Muniswamy, Criner, Gerard J., Bahmed, Karim
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711885/
https://ncbi.nlm.nih.gov/pubmed/31383554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.07.063
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