Mitochondrial dysfunction in human primary alveolar type II cells in emphysema

BACKGROUND: Cigarette smoke is the main risk factor of pulmonary emphysema development, which is characterized by alveolar wall destruction. Mitochondria are important for alveolar type II (ATII) cell metabolism due to ATP generation. METHODS: We isolated ATII cells from control non-smoker and smoke...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:EBioMedicine
Main Authors: Kosmider, Beata, Lin, Chih-Ru, Karim, Loukmane, Tomar, Dhanendra, Vlasenko, Liudmila, Marchetti, Nathaniel, Bolla, Sudhir, Madesh, Muniswamy, Criner, Gerard J., Bahmed, Karim
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Research paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6711885/
https://ncbi.nlm.nih.gov/pubmed/31383554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.07.063
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