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Unique and overlapping GLI1 and GLI2 transcriptional targets in neoplastic chondrocytes
Excessive Hedgehog (Hh) signaling in chondrocytes is sufficient to cause formation of enchondroma-like lesions which can progress to chondrosarcoma. To elucidate potential underlying mechanisms, we identified GLI1 and GLI2 target genes in human chondrosarcoma. Using chromatin immunoprecipitation (Ch...
Sparad:
| I publikationen: | PLoS One |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2019
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6350985/ https://ncbi.nlm.nih.gov/pubmed/30695055 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211333 |
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