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Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish

Hedgehog (Hh) signaling is mediated by the Gli transcription factors and, in the zebrafish, plays an important role in patterning both the neural tube and myotome. Using a null allele of the gli2a gene induced by targeted mutagenesis, we show that Gli2a is completely dispensable in the fish but acts...

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Библиографические подробности
Главные авторы: Wang, Xingang, Zhao, Zhonghua, Muller, Julius, Iyu, Audrey, Khng, Alexis Jiaying, Guccione, Ernesto, Ruan, Yijun, Ingham, Philip W.
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828767/
https://ncbi.nlm.nih.gov/pubmed/24244857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20136262
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