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Targeted inactivation and identification of targets of the Gli2a transcription factor in the zebrafish

Hedgehog (Hh) signaling is mediated by the Gli transcription factors and, in the zebrafish, plays an important role in patterning both the neural tube and myotome. Using a null allele of the gli2a gene induced by targeted mutagenesis, we show that Gli2a is completely dispensable in the fish but acts...

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Detalhes bibliográficos
Main Authors: Wang, Xingang, Zhao, Zhonghua, Muller, Julius, Iyu, Audrey, Khng, Alexis Jiaying, Guccione, Ernesto, Ruan, Yijun, Ingham, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3828767/
https://ncbi.nlm.nih.gov/pubmed/24244857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20136262
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