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Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion

Two clinically distinct diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), have recently been classified as two extremes of the FTD/ALS spectrum. The neuropathological correlate of FTD is frontotemporal lobar degeneration (FTLD), characterized by tau-, TDP-43-, and FUS-...

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Detalhes bibliográficos
Publicado no:Behav Neurol
Main Authors: Babić Leko, Mirjana, Župunski, Vera, Kirincich, Jason, Smilović, Dinko, Hortobágyi, Tibor, Hof, Patrick R., Šimić, Goran
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350563/
https://ncbi.nlm.nih.gov/pubmed/30774737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2909168
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