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Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion

Two clinically distinct diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), have recently been classified as two extremes of the FTD/ALS spectrum. The neuropathological correlate of FTD is frontotemporal lobar degeneration (FTLD), characterized by tau-, TDP-43-, and FUS-...

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Publicat a:Behav Neurol
Autors principals: Babić Leko, Mirjana, Župunski, Vera, Kirincich, Jason, Smilović, Dinko, Hortobágyi, Tibor, Hof, Patrick R., Šimić, Goran
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350563/
https://ncbi.nlm.nih.gov/pubmed/30774737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2909168
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