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Molecular Mechanisms of Neurodegeneration Related to C9orf72 Hexanucleotide Repeat Expansion

Two clinically distinct diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), have recently been classified as two extremes of the FTD/ALS spectrum. The neuropathological correlate of FTD is frontotemporal lobar degeneration (FTLD), characterized by tau-, TDP-43-, and FUS-...

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Dettagli Bibliografici
Pubblicato in:Behav Neurol
Autori principali: Babić Leko, Mirjana, Župunski, Vera, Kirincich, Jason, Smilović, Dinko, Hortobágyi, Tibor, Hof, Patrick R., Šimić, Goran
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350563/
https://ncbi.nlm.nih.gov/pubmed/30774737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2909168
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