Φορτώνει......
A Combination of Flow and Batch Mode Processes for the Efficient Preparation of mGlu(2/3) Receptor Negative Allosteric Modulators (NAMs)
Benzodiazepinones are privileged scaffolds with activity against multiple therapeutically relevant biological targets. In support of our ongoing studies around allosteric modulators of metabotropic glutamate receptors (mGlus) we required the multigram synthesis of a β-ketoester key intermediate. We...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Tetrahedron |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6349389/ https://ncbi.nlm.nih.gov/pubmed/30705468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2018.03.068 |
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