New Water-Soluble Copper(II) Complexes with Morpholine–Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action

[Image: see text] Six morpholine-(iso)thiosemicarbazone hybrids HL(1)–HL(6) and their Cu(II) complexes with good-to-moderate solubility and stability in water were synthesized and characterized. Cu(II) complexes [Cu(L(1–6))Cl] (1–6) formed weak dimeric associates in the solid state, which did not re...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Ohui, Kateryna, Afanasenko, Eleonora, Bacher, Felix, Ting, Rachel Lim Xue, Zafar, Ayesha, Blanco-Cabra, Núria, Torrents, Eduard, Dömötör, Orsolya, May, Nóra V., Darvasiova, Denisa, Enyedy, Éva A., Popović-Bijelić, Ana, Reynisson, Jóhannes, Rapta, Peter, Babak, Maria V., Pastorin, Giorgia, Arion, Vladimir B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348444/
https://ncbi.nlm.nih.gov/pubmed/30507173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.8b01031
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