Triapine Derivatives Act as Copper Delivery Vehicles to Induce Deadly Metal Overload in Cancer Cells

Thiosemicarbazones continue to attract the interest of researchers as potential anticancer drugs. For example, 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, or triapine, is the most well-known representative of this class of compounds that has entered multiple phase I and II clinical trials. T...

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Pubblicato in:Biomolecules
Autori principali: Ohui, Kateryna, Stepanenko, Iryna, Besleaga, Iuliana, Babak, Maria V., Stafi, Radu, Darvasiova, Denisa, Giester, Gerald, Pósa, Vivien, Enyedy, Eva A., Vegh, Daniel, Rapta, Peter, Ang, Wee Han, Popović-Bijelić, Ana, Arion, Vladimir B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564244/
https://ncbi.nlm.nih.gov/pubmed/32961653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10091336
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