Single-cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment

Knowledge of immune cell phenotypes in the tumor microenvironment is essential for understanding mechanisms of cancer progression and immunotherapy response. We profiled 45,000 immune cells from eight breast carcinomas, as well as matched normal breast tissue, blood, and lymph node, using single-cel...

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Pubblicato in:Cell
Autori principali: Azizi, Elham, Carr, Ambrose J., Plitas, George, Cornish, Andrew E., Konopacki, Catherine, Prabhakaran, Sandhya, Nainys, Juozas, Wu, Kenmin, Kiseliovas, Vaidotas, Setty, Manu, Choi, Kristy, Fromme, Rachel M., Dao, Phuong, McKenney, Peter T., Wasti, Ruby C., Kadaveru, Krishna, Mazutis, Linas, Rudensky, Alexander Y., Pe’er, Dana
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6348010/
https://ncbi.nlm.nih.gov/pubmed/29961579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.05.060
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