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The RNA degradosome promotes tRNA quality control through clearance of hypomodified tRNA

The factors and mechanisms that govern tRNA stability in bacteria are not well understood. Here, we investigated the influence of posttranscriptional modification of bacterial tRNAs (tRNA modification) on tRNA stability. We focused on ThiI-generated 4-thiouridine (s(4)U), a modification found in bac...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kimura, Satoshi, Waldor, Matthew K.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347707/
https://ncbi.nlm.nih.gov/pubmed/30622183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814130116
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