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Comparative tRNA sequencing and RNA mass spectrometry for surveying tRNA modifications

Chemical modifications of the nucleosides that comprise tRNAs are diverse. However, the structure, location, and extent of modifications have been systematically charted in very few organisms. Here, we describe an approach in which rapid prediction of modified sites through reverse transcription-der...

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Vydáno v:Nat Chem Biol
Hlavní autoři: Kimura, Satoshi, Dedon, Peter C., Waldor, Matthew K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8172280/
https://ncbi.nlm.nih.gov/pubmed/32514182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-020-0558-1
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