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The conserved aspartate ring of MCU mediates MICU1 binding and regulation in the mitochondrial calcium uniporter complex
The mitochondrial calcium uniporter is a Ca(2+) channel that regulates intracellular Ca(2+) signaling, oxidative phosphorylation, and apoptosis. It contains the pore-forming MCU protein, which possesses a DIME sequence thought to form a Ca(2+) selectivity filter, and also regulatory EMRE, MICU1, and...
Tallennettuna:
| Julkaisussa: | eLife |
|---|---|
| Päätekijät: | , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
eLife Sciences Publications, Ltd
2019
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6347451/ https://ncbi.nlm.nih.gov/pubmed/30638448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41112 |
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