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Mechanism and regulation of DNA damage recognition in nucleotide excision repair

Nucleotide excision repair (NER) is a versatile DNA repair pathway, which can remove an extremely broad range of base lesions from the genome. In mammalian global genomic NER, the XPC protein complex initiates the repair reaction by recognizing sites of DNA damage, and this depends on detection of d...

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Bibliographische Detailangaben
Veröffentlicht in:Genes Environ
Hauptverfasser: Kusakabe, Masayuki, Onishi, Yuki, Tada, Haruto, Kurihara, Fumika, Kusao, Kanako, Furukawa, Mari, Iwai, Shigenori, Yokoi, Masayuki, Sakai, Wataru, Sugasawa, Kaoru
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346561/
https://ncbi.nlm.nih.gov/pubmed/30700997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41021-019-0119-6
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