PD-L1 Expression in Circulating Tumor Cells Increases during Radio(chemo)therapy and Indicates Poor Prognosis in Non-small Cell Lung Cancer

Preclinical studies demonstrated that radiation up-regulates PD-L1 expression in tumor cells, providing a rationale for combining PD-1/PD-L1 inhibitors with radiation. However this has not been validated in patients with non-small cell lung cancer due to the difficulty to obtain serial biopsies. Mea...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Wang, Yang, Kim, Tae Hyun, Fouladdel, Shamileh, Zhang, Zhuo, Soni, Payal, Qin, Angel, Zhao, Lili, Azizi, Ebrahim, Lawrence, Theodore S., Ramnath, Nithya, Cuneo, Kyle C., Nagrath, Sunitha
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345864/
https://ncbi.nlm.nih.gov/pubmed/30679441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36096-7
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki