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Expanded CTCs from a Patient with ALK Positive Lung Cancer Present EML4-ALK Rearrangement along with Resistance Mutation and Enable Drug Sensitivity Testing: A Case Study

The emergence of liquid biopsy using circulating tumor cells (CTCs) as a resource to identify genomic alterations in cancer presents new opportunities for diagnosis, therapy and surveillance. The presented study identified EML4-ALK gene rearrangement in expanded CTCs from one ALK positive lung adeno...

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Detalhes bibliográficos
Publicado no:J Thorac Oncol
Main Authors: Zhang, Zhuo, Shiratsuchi, Hiroe, Palanisamy, Nallasivam, Nagrath, Sunitha, Ramnath, Nithya
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5263096/
https://ncbi.nlm.nih.gov/pubmed/27507192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtho.2016.07.027
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