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Simultaneous Single Cell Gene Expression and EGFR Mutation Analysis of Circulating Tumor Cells Reveals Distinct Phenotypes in NSCLC

While cancer cell populations are known to be highly heterogeneous within a tumor, the current gold standard of tumor profiling is through a tumor biopsy. These biopsies are invasive and prone to missing these clones due to spatial heterogeneity, and this bulk analysis approach can miss information...

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Detalhes bibliográficos
Publicado no:Adv Biosyst
Main Authors: Owen, Sarah, Lo, Ting-Wen, Fouladdel, Shamileh, Zeinali, Mina, Keller, Evan, Azizi, Ebrahim, Ramnath, Nithya, Nagrath, Sunitha
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883301/
https://ncbi.nlm.nih.gov/pubmed/32700450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.202000110
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