Simultaneous Single Cell Gene Expression and EGFR Mutation Analysis of Circulating Tumor Cells Reveals Distinct Phenotypes in NSCLC

While cancer cell populations are known to be highly heterogeneous within a tumor, the current gold standard of tumor profiling is through a tumor biopsy. These biopsies are invasive and prone to missing these clones due to spatial heterogeneity, and this bulk analysis approach can miss information...

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Gepubliceerd in:Adv Biosyst
Hoofdauteurs: Owen, Sarah, Lo, Ting-Wen, Fouladdel, Shamileh, Zeinali, Mina, Keller, Evan, Azizi, Ebrahim, Ramnath, Nithya, Nagrath, Sunitha
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7883301/
https://ncbi.nlm.nih.gov/pubmed/32700450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adbi.202000110
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