Liver Derived FGF21 Maintains Core Body Temperature During Acute Cold Exposure

Fibroblast Growth Factor 21 (FGF21) elicits an array of metabolic effects. However, the physiological role of FGF21 during thermal challenges is not clear. In this study, we assessed the tissue source of FGF21 and its site of action to regulate core body temperature in response to cold. Using mice l...

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Udgivet i:Sci Rep
Main Authors: Ameka, Magdalene, Markan, Kathleen R., Morgan, Donald A., BonDurant, Lucas D., Idiga, Sharon O., Naber, Meghan C., Zhu, Zhiyong, Zingman, Leonid V., Grobe, Justin L., Rahmouni, Kamal, Potthoff, Matthew J.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345819/
https://ncbi.nlm.nih.gov/pubmed/30679672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37198-y
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