Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding

Fibroblast growth factor (FGF)21 is an endocrine hormone that is expressed in multiple tissues and functions physiologically to maintain energy homeostasis. FGF21 is being pursued as a therapeutic target for diabetes and obesity because of its rapid and potent effects on improving insulin sensitivit...

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Опубликовано в: :Diabetes
Главные авторы: Markan, Kathleen R., Naber, Meghan C., Ameka, Magdalene K., Anderegg, Maxwell D., Mangelsdorf, David J., Kliewer, Steven A., Mohammadi, Moosa, Potthoff, Matthew J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2014
Предметы:
Metabolism
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238010/
https://ncbi.nlm.nih.gov/pubmed/25008183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0595
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