Circulating FGF21 Is Liver Derived and Enhances Glucose Uptake During Refeeding and Overfeeding

Fibroblast growth factor (FGF)21 is an endocrine hormone that is expressed in multiple tissues and functions physiologically to maintain energy homeostasis. FGF21 is being pursued as a therapeutic target for diabetes and obesity because of its rapid and potent effects on improving insulin sensitivit...

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Bibliografiske detaljer
Udgivet i:Diabetes
Main Authors: Markan, Kathleen R., Naber, Meghan C., Ameka, Magdalene K., Anderegg, Maxwell D., Mangelsdorf, David J., Kliewer, Steven A., Mohammadi, Moosa, Potthoff, Matthew J.
Format: Artigo
Sprog:Inglês
Udgivet: American Diabetes Association 2014
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4238010/
https://ncbi.nlm.nih.gov/pubmed/25008183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-0595
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