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FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue

OBJECTIVE: Fibroblast growth factor 21 (FGF21) is an endocrine hormone that regulates metabolic homeostasis. Previous work has suggested that impairment of FGF21 signaling in adipose tissue may occur through downregulation of the obligate FGF21 co-receptor, β-klotho, which leads to “FGF21 resistance...

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Dettagli Bibliografici
Pubblicato in:Mol Metab
Autori principali: Markan, Kathleen R., Naber, Meghan C., Small, Sarah M., Peltekian, Lila, Kessler, Rachel L., Potthoff, Matthew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5444074/
https://ncbi.nlm.nih.gov/pubmed/28580290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.03.009
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