BBSome ablation in SF1 neurons causes obesity without comorbidities

OBJECTIVES: The hypothalamic ventromedial nucleus (VMH) plays a major role in metabolic control, but the molecular mechanisms involved remain poorly defined. We analyzed the relevance of the BBSome, a protein complex composed of 8 Bardet–Biedl syndrome (BBS) proteins including BBS1, in VMH steroidog...

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Detalles Bibliográficos
Publicado en:Mol Metab
Autores principales: Rouabhi, Mohamed, Guo, Deng-Fu, Morgan, Donald A., Zhu, Zhiyong, López, Miguel, Zingman, Leonid, Grobe, Justin L., Rahmouni, Kamal
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2021
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8065214/
https://ncbi.nlm.nih.gov/pubmed/33722691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2021.101211
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