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Development of Multitarget Agents Possessing Soluble Epoxide Hydrolase Inhibitory Activity
Over the last two decades polypharmacology has emerged as a new paradigm in drug discovery, even though developing drugs with high potency and selectivity toward a single biological target is still a major strategy. Often, targeting only a single enzyme or receptor shows lack of efficacy. High level...
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| Udgivet i: | Prostaglandins Other Lipid Mediat |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6345559/ https://ncbi.nlm.nih.gov/pubmed/30593866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2018.12.003 |
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