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The OTUD5–UBR5 complex regulates FACT-mediated transcription at damaged chromatin
Timely stalling and resumption of RNA polymerases at damaged chromatin are actively regulated processes. Prior work showed an importance of FACT histone chaperone in such process. Here we provide a new role of OTUD5 deubiquitinase in the FACT-dependent process. Through a DUB RNAi screen, we found OT...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6344881/ https://ncbi.nlm.nih.gov/pubmed/30508113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky1219 |
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