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Large-scale organization of ribosomal DNA chromatin is regulated by Tip5
The DNase I accessibility and chromatin organization of genes within the nucleus do correlate to their transcriptional activity. Here, we show that both serum starvation and overexpression of Tip5, a key regulator of ribosomal RNA gene (rDNA) repression, dictate DNase I accessibility, facilitate the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3664807/ https://ncbi.nlm.nih.gov/pubmed/23580549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt218 |
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