Large-scale organization of ribosomal DNA chromatin is regulated by Tip5

The DNase I accessibility and chromatin organization of genes within the nucleus do correlate to their transcriptional activity. Here, we show that both serum starvation and overexpression of Tip5, a key regulator of ribosomal RNA gene (rDNA) repression, dictate DNase I accessibility, facilitate the...

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Bibliografske podrobnosti
Main Authors: Zillner, Karina, Filarsky, Michael, Rachow, Katrin, Weinberger, Michael, Längst, Gernot, Németh, Attila
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Gene Regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664807/
https://ncbi.nlm.nih.gov/pubmed/23580549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt218
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